"Fantastic chemical cocktail with potential medical applications unequaled by any other amphibian"
- Vittorio Erspamer
What is Kambo?
Kambo is the secretion of the Phyllomedusa Bicolor, or more commonly known as the Giant Green Monkey Tree Frog, found in many regions throughout the Upper Amazonian rainforests. Given that this frog has no natural predators and is a prolific breeder with a single spawn of one female averaging 1,000 eggs, they are found in abundance, and the ICUN database lists them in the 'Least Concern’ category. The potential destruction of their habitat and spawn predation are the only known threats.
The secretion of Kambo is a highly unique and complex treasure trove of peptides, neuropeptides and bioactive peptides, which are all short chains of amino acids, the building blocks of all human life. In the 1986 Vittorio Erspamer, an Italian scientist of the University of Rome, was the first to analyze Kambo in a lab setting. He concluded that Kambo contains a 'fantastic chemical cocktail with potential medical applications unequaled by any other amphibian.' Espamer's sixty year career included two Nobel prize nominations and innumerable important contributions, including the isolation and discovery of numerous different compounds, many of them from animals, with the majority from amphibians. His lab work focused on peptides specific to the Phyllomedusa Bicolor brought some understanding to the positive impact Kambo has on the human body. He highlighted its ability, unlike most other natural substances and pharmaceuticals, to pass through the blood brain barrier, as well as its capacity to also act like a key to unlock individual cell receptor sites that allow the entry of this 'fantastic chemical cocktail,' enabling its healthful properties to deeply cleanse and detox the human body.
To date researchers have identified nine families of peptides in Kambo. These nine families of peptides include bioactive peptides, neuropeptides, heptapeptides and polypeptides. Each of these have different effects in the human body, some of which include: potent analgesic properties, long lasting reduction in blood pressure, high potency against the yeast Candid Albicans, potent antimicrobial activity against drug-resistant strains of bacteria, yeast, fungi, parasites and enveloped viruses as well as various filamentous fungi that are responsible for severe opportunistic infections accompanying AIDS. Additionally, there are effective components for killing certain types of cancer cells, anti-inflammatory properties, and potent vessel dilation making the blood brain barrier more permeable. This in no way is an exhaustive list, rather a general idea of the amazing potential that exists in Kambo.
Interestingly due to the medicinal values discovered in the above mentioned peptides, many have been synthesized and are now available for sale online. Additionally, over 70 Kambo patents have been logged, mostly in the United States.